Figure 4
From: Expression of canonical WNT/β-CATENIN signaling components in the developing human lung
Expression of canonical WNT/β-CATENIN transducers in the developing human lung. Sections of the human embryos at the gestational ages of 7 W, 12 W, 17 W and 21 W (W: Weeks of gestation) showed particular expression of canonical WNT signal transducers DVL2 ( A- D), GSK-3β ( I- L) and APC ( Q- T) in the distal epithelium. However, the expression of WNT signal transducers DVL3 ( E- H), CTNNB1 (also β-CATENIN, M- P) and AXIN2 ( U- X) was detected mainly in the distal epithelium and also weakly in the mesenchyme of human embryonic lungs at the gestational age of 7 W, 12 W, 17 and 21 W. Scale bars = 100 μm in A- X.