Table 1 Downregulated genes in PM/PM versus wt thyroid at E18
From: In vivo role of different domains and of phosphorylation in the transcription factor Nkx2-1
Gene Symbol | Gene Title | Fold decrease | Gene onthology category |
|---|---|---|---|
LOC432613 | Trim47 | -11,6 | protein ubiquination |
Ager | advanced glycosylation end product-specific receptor | -11,3 | transport/receptor |
Scgb1a1 | secretoglobin, family 1A, member 1 (uteroglobin) | -8,0 | steroid binding phospholipase A2 inhibitor activity |
Narg2 | NMDA receptor-regulated gene 2 | -7,2 | DNA binding |
Calca | calcitonin/calcitonin-related polypeptide, alpha | -7,2 | hormone |
Nkx2-2 | Nkx2-2 | -7,1 | regulation of transcription |
Iyd | iodotyrosine deiodasi | -5,8 | |
Elovl2 | elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 2 | -5,5 | fatty acid biosynthesis |
Cdh16 | cadherin 16 | -4,9 | cell adhesion |
S100a5 | S100 calcium binding protein A5 | -4,7 | calcium ion binding |
Lsm11 | U7 snRNP-specific Sm-like protein LSM11 | -4,2 | mRNA processing |
3830431G21 | RIKEN cDNA | -4,2 | --- |
Ero1lb | Ero1-like beta | -4,2 | electron transport |
Klk10 | kallikrein 10 | -4,1 | proteolysis and peptidolysis |
Acad8 | acyl-Coenzyme A dehydrogenase family, member 8 | -4,1 | electron transport |
2810055F11 | putative proline racemase | -3,5 | |
Napsa | napsin A aspartic peptidase | -3,3 | proteolysis and peptidolysis |
Tgn | thyroglobulin | -3,3 | thyroid hormone generation |
Clic3 | chloride intracellular channel 3 | -3,3 | ion transport |
Folr1 | folate receptor 1 (adult) | -3,1 | folic acid metabolism |
Sall1 | --- | -3,0 | regulation of transcription |
Tmem213 | transmembrane protein 213 | -3,0 | --- |
Nkd1 | naked cuticle 1 homolog (Drosophila) | -3,0 | calcium ion binding |
2410146L05 | RIKEN cDNA | -3,0 | --- |
6530415H11 | RIKEN cDNA | -3,0 | --- |
Cldn6 | claudin 6 | -2,9 | cell adhesion |
Rhof | ras homolog gene family, member f | -2,7 | GTPase mediated signal transduction |
Prdm1 | PR domain containing 1, with ZNF domain | -2,7 | regulation of transcription |
Mt1 | metallothionein 1 | -2,6 | metal ion homeostasis |
Mt2 | metallothionein 2 | -2,6 | metal ion homeostasis |
Arg2 | arginase type II | -2,5 | arginine metabolism |
Nprl2-pending | Tusc4 | -2,5 | cell cycle |
Slain1 | SLAIN motif family, member 1 | -2,5 | --- |
Zfp28 | zinc finger pt 28 | -2,5 | regulation of transcription |
Smarca1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 | -2,4 | transcription regulator activity/chromatin modification |
Vldlr | very low density lipoprotein receptor | -2,3 | lipid transport |
Rbpms | RNA binding protein gene with multiple splicing | -2,3 | RNA binding |
Transcribed locus | 135334_f_at | -2,1 | --- |
Atp5j2 | ATP synthase, H+ transporting, mitochondrial F0 complex, subunit f, isoform 2 | -2,1 | ion transport |
Cited4 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4 | -2,0 | transcription coactivator |
Zfp26 | zinc finger protein 26 | -2,0 | DNA binding |