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Figure 5 | BMC Developmental Biology

Figure 5

From: Conserved and non-conserved enhancers direct tissue specific transcription in ancient germ layer specific developmental control genes

Figure 5

foxa2 CNEs and modified BAC. (A) UCSC browser snapshot showing synteny around foxa2 and the functional CNEs Fx2 and Fx6. (B) Whole mount RNA in situ hybridization at 48 hpf shows foxa2 expression in the rostral part covering forebrain and pharyngeal endoderm (C) Section in situ hybridization showing expression of foxa2 in forebrain at 48 hpf. (D) Section in situ hybridization showing expression of foxa2 in pharyngeal endoderm at 48 hpf. (E) Modified BAC showing expression in forebrain and (F) pharyngeal endoderm at 48 hpf.(G) CNE Fx2 and (H) Fx6 drives expression in the forebrain at 48 hpf. FB - forebrain. PE - pharyngeal endoderm

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