Figure 11

Plastic sections of the P10 WT and Lama1^nmf223 eyes. JB-4 cross sections revealed the diving of superficial retinal vessels (paired arrows) in the WT retina (A, B). In the Lama1^nmf223 retinas, astrocytes (arrowheads) and blood vessels (paired arrows) were in the vitreous and entering the retina (C, D). TEM confirms the presence of astrocytes (arrowhead) and blood vessels (arrow) in the vitreous (E) with intermediate filaments evident in astrocytes at high magnification (F). Scale bars indicate (A-D: 20 μm; E: 3 μm; F: 250 nm).