Figure 7
Ectopic aPKC signaling impairs Hippo pathway signaling even when JNK signaling is blocked. Larval eye/antennal discs with ey-FLP induced mutant clones marked by GFP expression (green, or magenta in the merges). Grayscale is β-GAL and F-actin. A white bar indicates the location of the MF. Apical (A, C) and basal (B, D) confocal sections are shown. (A-D) Coexpression of aPKCΔN with bskDN in clones results in large masses of tissue extruded basally from the epithelium which ectopically express ex-lacZ (A, B; arrows) and fj-lacZ (C, D; arrows).