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Table 1 Densities of rod and cone photoreceptors in control and RA-treated embryos, and in theoretical datasets

From: Plasticity of photoreceptor-generating retinal progenitors revealed by prolonged retinoic acid exposure

 

Cell densities (cells/3600 μm2)

 

60 hpf

75 hpf

Cell Type

Control

RA

Control

RA

Rods

9.56 ± 2.55

19.2 ± 6.75**

16.2 ± 2.68

N.D.a

Cones:

    

Red

70.5 ± 12.69

53.33 ± 13.42*

59.50 ± 8.23

28.40 +8.53***

Blue

45.44 ± 5.66

37.1 ± 8.30*

52.56 ± 18.56

38.33 ± 10.71*

UV

47.33 ± 6.96

40.11 ± 5.80*

N.D.

N.D

 

Theoretical red cone loss (n = 5) b

 

25% loss

50% loss

25% loss

50% loss

 

48.4 ± 10.81**

32.40 ± 7.5***

43.20 ± 7.53**

29.40 ± 5.81***

  1. *p < 0.05; **p < 0.01; ***p < 0.001 (Student's t-test).
  2. N.D. = Not done.
  3. a Rod density was so high as to preclude accurate counting.
  4. b As compared to red cone density at 75 hpf.