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Table 2 mRNA levels for genes related myogenesis, chondrogenesis, and osteogenesis in NTC- and BMP-2 siRNA-treated tongues

From: Bone morphogenetic protein-2 functions as a negative regulator in the differentiation of myoblasts, but not as an inducer for the formations of cartilage and bone in mouse embryonic tongue

Genes

NTC

BMP-2 siRNA

Significance

Myogenesis

   

MyoD

0.0130 ± 0.00452

0.0136 ± 0.00515

NS

Myogenin

0.0128 ± 0.0044

0.0203 ± 0.0037

p < 0.01

MCK

0.0646 ± 0.0251

0.116 ± 0.0275

p < 0.01

Chondrogenesis, osteogenesis

   

Runx2

0

0

NS

Osteocalcin

0.0000406 ± 0.0000632

0.0000356 ± 0.0000795

NS

ALP

0.00291 ± 0.00455

0.00365 ± 0.00460

NS

Collagen II

0.000202 ± 0.000333

0.0000435 ± 0.0000529

NS

Collagen X

0.000674 ± 0.000690

0.000264 ± 0.000265

NS

  1. The mean ± standard deviation of six vehicle-treated or six BMP-2-treated tongues for each gene is shown. The ratio of each target gene mRNA relative to GAPDH mRNA is shown.