Genes
|
Vehicle
|
Recombinant BMP-2
|
Significance
|
---|
Myogenesis
| | | |
MyoD
|
0.0163 ± 0.00616
|
0.0172 ± 0.00467
|
NS
|
Myogenin
|
0.0256 ± 0.00510
|
0.0180 ± 0.00162
|
p < 0.01
|
MCK
|
0.0661 ± 0.0149
|
0.0414 ± 0.00737
|
p < 0.01
|
Chondrogenesis, osteogenesis
| | | |
Runx2
|
0
|
0.0000661 ± 0.0000800
|
NS
|
Osteocalcin
|
0.0000514 ± 0.0000552
|
0.0000581 ± 0.0000535
|
NS
|
ALP
|
0.000813 ± 0.000632
|
0.000700 ± 0.000576
|
NS
|
Collagen II
|
0.000167 ± 0.00246
|
0.000535 ± 0.0105
|
NS
|
Collagen X
|
0.000129 ± 0.00123
|
0.000155 ± 0.00168
|
NS
|
- The mean ± standard deviation of six vehicle-treated or six BMP-2-treated tongues for each gene is shown. The ratio of each target gene mRNA relative to GAPDH mRNA is shown.