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Table 1 mRNA levels for genes related to myogenesis, chondrogenesis, and osteogenesis in vehicle- and BMP-2-treated tongues

From: Bone morphogenetic protein-2 functions as a negative regulator in the differentiation of myoblasts, but not as an inducer for the formations of cartilage and bone in mouse embryonic tongue

Genes Vehicle Recombinant BMP-2 Significance
Myogenesis    
MyoD 0.0163 ± 0.00616 0.0172 ± 0.00467 NS
Myogenin 0.0256 ± 0.00510 0.0180 ± 0.00162 p < 0.01
MCK 0.0661 ± 0.0149 0.0414 ± 0.00737 p < 0.01
Chondrogenesis, osteogenesis    
Runx2 0 0.0000661 ± 0.0000800 NS
Osteocalcin 0.0000514 ± 0.0000552 0.0000581 ± 0.0000535 NS
ALP 0.000813 ± 0.000632 0.000700 ± 0.000576 NS
Collagen II 0.000167 ± 0.00246 0.000535 ± 0.0105 NS
Collagen X 0.000129 ± 0.00123 0.000155 ± 0.00168 NS
  1. The mean ± standard deviation of six vehicle-treated or six BMP-2-treated tongues for each gene is shown. The ratio of each target gene mRNA relative to GAPDH mRNA is shown.
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BMC Developmental Biology

ISSN: 1471-213X

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