Table 1 Binding specificities of HS antibodies and characteristics of the recognised epitopes, extracted from [24]
Antibody | Sulfation preference | Disulfated preference | Binds monosulfated? | Oligosaccharide length required for significant binding |
|---|---|---|---|---|
HS3B7V | Hep > 2S,NS > 6S,NS > HS > 6S,2S > 6S > 2S | 2S, NS or 6S, NS | 2S or 6S | >dp10 |
HS4E4V | HS > 6S,NS = 2S,NS > Hep > 6S > 6S,2S | 2S, NS or 6S, NS | Only 6S | dp8 |
HS3A8V | Hep > 2S,NS = HS > 6S,NS > 6S > 6S,2S | 2S, NS | Only 6S | dp6 |
AO4B08V | Hep > HS > 2S,NS > 6S > NS,6S > 6S,2S > 2S | 2S, NS | 2S or 6S | dp4 |
EV3C3V | Hep > 2S,NS > HS > 6S,NS > 6S,2S ≥ 6S | 2S, NS | Only 6S | dp8 |
EW4G1V | Hep > 2S,NS > HS > 6S,NS ≥ 6S,2S = 6S > 2S | 2S, NS | 2S or 6S | dp8 |