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Figure 2 | BMC Developmental Biology

Figure 2

From: Structure and epitope distribution of heparan sulfate is disrupted in experimental lung hypoplasia: a glycobiological epigenetic cause for malformation?

Figure 2

Different compartments of the lung display distinct HS epitopes e.g., airway epithelium. Airway epithelial cells display HS epitopes identified by EV3C3V, AO4B08V and HS3A8V. At E13.5, only the EV3C3V epitope is present and at E15.5, AO4B08V and HS3A8V epitopes are additionally displayed. HS structures recognised by HS3B7V, HS4E4V and EW4G1V are not identified in the epithelium at any developmental stage. E13.5 and E15.5 rat lungs were probed with HS antibodies followed by rabbit VSV-G tag antibody and FITC conjugated goat anti-rabbit IgG. Scale bar represents 10 μm and all images are the same magnification. (ep) epithelium, (me) mesenchyme.

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BMC Developmental Biology

ISSN: 1471-213X

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