Expression of miR-1, miR-133a, miR-133b and miR-206 increases during development of human skeletal muscle

Table 1 Statistical analysis of muscle miRNA expression levels during muscle foetal development

		miR-1 ΔCt	miR-133a ΔCt	miR-133b ΔCt	miR-206 ΔCt
Comparison between confluent and differentiated cells	12 weeks	p < 0.05	p < 0.05	p < 0.05	p < 0.05
	14 weeks	p < 0.05	p < 0.05	p < 0.05	p < 0.05
	Newborn	p < 0.05	p < 0.05	p < 0.05	p < 0.05
Comparison between confluent and differentiated cells (all developmental stages combined)		p < 0.0001	p < 0.0001	p < 0.0001	p < 0.0001
Comparison between developmental stages (differentiated cells)		p < 0.05	p < 0.05	p < 0.005	p < 0.005

Comparison of miRNA levels between confluent and differentiated muscle cells at each developmental stage or combined was performed. Comparison of miRNA levels between developmental stages of differentiated muscle cells was carried out. All results were statistically significant (p-value < 0.05).

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