Figure 3
Clustering based on decreasing gene expression profiles across the four developmental stages. Three clusters display a decrease in transcript abundance during development. A) Cluster 3 transcripts (dnmt1, plk1, plk3, slc16a3 and slc25a25 among others) are moderately expressed in early development and decrease to relatively low levels in 50% epiboly. B) Transcripts in cluster 6 are detected at relatively high RPKM levels during early development. C) Cluster 8 transcripts (ccna1, cldn d, ctssb.1, fth1, gapdh, gmnn, mid1ip1, mt2 and zgc:110304 among others) are highly abundant in 1-cell to 512-cell stage.