The MAP kinase ERK and its scaffold protein MP1 interact with the chromatin regulator Corto during Drosophilawing tissue development

Table 3 corto interacts with rolled (rl) and dMP1 during wing tissue differentiation

Genotype	Total females observed	% females with ectopic veins only	% females with one blistered wing	% females with two blistered wings
sd::Gal4/+;+/UAS::rl ^Sem	108	12	40.7	47.3
sd::Gal4/+;corto ⁴²⁰ /UAS::rl ^Sem	85	50.6 ^a	36.5	12.9 ^a
sd::Gal4/+;corto ^07128b /UAS::rl ^Sem	78	44.9 ^a	44.9	10.2 ^a
+/sd::Gal4; UAS::dsMP1/+	158	78.5	0	0
+/sd::Gal4; UAS::dsMP1/+; +/corto ⁴²⁰	90	92.2 ^b	0	0
+/sd::Gal4; UAS::dsMP1/+; +/corto ^07128b	92	100	0	0

For all genotypes, the first allele was brought by the mother. Only female phenotypes are reported here, but similar results were obtained for males. Numbers of females with ectopic veins only or with two blistered wings among flies bearing a corto allele and over-expressing rl^Sem were compared to the one of flies over-expressing rl^Sem only. Numbers of females with ectopic veins among flies containing the UAS::dsMP1 transgene, the sd::Gal4 transgene and a corto mutation were compared to that of flies containing the UAS::dsMP1 and the sd::Gal4 transgenes only (Z-test, ^a p < 0.001; ^b p < 0.05).

ISSN: 1471-213X