The MAP kinase ERK and its scaffold protein MP1 interact with the chromatin regulator Corto during Drosophilawing tissue development

Table 1 corto mutants induce ectopic vein phenotypes and interact with blistered (bs) and rhomboïd (rho) during wing tissue differentiation

Genotype	Total females observed	% females with ectopic veins only	% females with blistered wings
corto ⁴²⁰ /+	70	8.6	0
+/corto ⁴²⁰	45	2.2	0
corto ^L1 /+	51	49	0
+/corto ^L1	90	52.2	0
corto ^07128b /+	78	97.4	0
+/corto ⁰⁷¹²⁸	46	97.8	0
+/bs^EY23316	136	100	0
+/bs^EY23316 ; corto^07128b/+	80	67.5	32.5^a
+/rho^EP3704	68	0	0
sd::Gal4/+; +/rho ^EP3704	105	90.5	9.5
sd::Gal4/+; corto⁴²⁰ /rho^EP3704	34	58.8	41.2 ^a
sd::Gal4/+; corto ^07128b /rho ^EP3704	90	51.1	48.9 ^a

For all genotypes, the first allele was brought by the mother. Only female phenotypes are reported here, but similar results were obtained for males. Numbers of females with blistered wings in flies containing a corto mutation and the bs^EY23316 or rho^EP3704 allele were compared to those of flies containing the bs^EY23316 or rho^EP3704 allele only (Z-test, ^a p < 0.001).

ISSN: 1471-213X