Figure 6
Expression of cardiac- and ES cell-specific transcripts. A. Comparison of expression levels of 42 known cardiac transcripts in iPS-BCs and ES-BCs. Data are presented as mean gene expression of triplicate samples in relative intensity units. Expression levels of all transcripts were not statistically significant between iPS-BCs and ES-BCs (p > 0,05). For genes, such as HAND1, MYL3 or TBX2, the mean intensity values strongly differ, but the difference is not statistically significant because of high variability in triplicate samples. B. Heat map presentation of expression levels of 27 ES cell-specific genes. Among all genes, only the expression of CYP26A1, NANOG and ABHD9 was statistically different between undifferentiated and differentiated iPS and ES cells. Data for additional CM- and ES cell-specific genes are given in the Additional file 6, Tables S12-S14.