Figure 4

Global transcriptional analysis of human iPS and ES cells and their corresponding beating clusters. A. Principal component analysis of 4254 variant genes. B. Hierarchical clustering analysis of variant genes. C. Scatter-plots comparing global gene expression profiles between undifferentiated ES and iPS cells, iPS-BCs and ES-BCs and undifferentiated iPS cells and iPS-BCs. D. The number of differentially expressed genes (p < 0.05, 2- fold change) in various intergroup comparisons. E. Venn diagram of iPS cell-upregulated (compared to ES cells) and iPS-BC-upregulated (compared to ES-BCs) transcripts and the number of overlapping genes. The p-value has been calculated using the Fisher's exact test.