Figure 1

Whole genome expression analysis of cut (C) and uncut (NC) wing imaginal discs after 24 hours. (A) Gene ontology (GO) terms of upregulated (red) or downregulated (green) genes. The number of genes in each category in the microarrays is shown within the bars. The length of the bars indicates the fold change (enrichment in these transcriptomes compared to the whole genome, P value < 0.001 in all cases). (B) Enrichment plots for statistically significant GO categories. (Top) The Enrichment Score (ES) computed by GSEA is shown for each category. ES value reaches its absolute peak on the left side of the enrichment plot, indicating overrepresentation in C0→C24 compared with NC0→NC24. The zero cross mark indicates the point in which the difference between expression in C0→C24 and NC0→NC24 is 0. (Bottom) Coloured bars illustrate the position of genes belonging to each GO category ranked according to their expression values in C and NC discs.