Different substrate treatment | Total embryo treated in one-cell stage†| No.(%) of survival embryo after treatment | No.(%) of embryos developed to | ||||
---|---|---|---|---|---|---|---|
 |  |  | 2-cell embryo | 4-cell embryo | 8-cell embryo | Morula embryo | Blastocyst embryo |
2 mM granzyme G Morpholino | 80 | 43(53.8) | 39(90.7)a | 5(11.6)a | 0(0.0)a | 0(0.0)a | 0(0.0)a |
2 mM control Morpholino | 90 | 45(50.0) | 45(100.0)ab | 42(93.3)b | 42(93.3)b | 37(82.2)b | 26(57.8)b |
M2 buffer injection | 46 | 20(43.5) | 20(100.0)ab | 17(85.0)b | 17(85.0)bc | 17(85.0)b | 17(85.0)c |
Control embryo (Uninjected) | 74 | -- | 74(100.0)b | 70(94.6)b | 57(77.0)c | 57(77.0)b | 57(77.0)bc |