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Table 1 Intercrosses between chuzhoi and Vangl2Lp/+, ScribCrc/+and Celsr1Crsh/+ generate offspring in the expected Mendelian ratios

From: The novel mouse mutant, chuzhoi, has disruption of Ptk7 protein and exhibits defects in neural tube, heart and lung development and abnormal planar cell polarity in the ear

Cross: Crc/+ × chz/+

     

Embryo genotypes

+/+;+/+

Crc/+;+/+

+/+; chz/+

Crc/+;chz/+

Total

Observed (expected) no. embryos

50 (39.5)

37 (39.5)

40 (39.5)

31 (39.5)

158

Cross: Crsh/+ × chz/+

     

Embryo genotypes

+/+;+/+

Crsh/+;+/+

+/+; chz/+

Crsh/+;chz/+

Total

Observed (expected) no. embryos

44 (38.25)

43 (38.25)

33 (38.25)

33 (38.25)

153

Cross: Lp/+ × chz/+

     

Embryo genotypes

+/+;+/+

Lp/+;+/+

+/+; chz/+

Lp/+;chz/+

Total

Observed (expected) no. embryos

39 (32.75)

30 (32.75)

27 (32.75)

35 (32.75)

131