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Figure 9 | BMC Developmental Biology

Figure 9

From: The novel mouse mutant, chuzhoi, has disruption of Ptk7 protein and exhibits defects in neural tube, heart and lung development and abnormal planar cell polarity in the ear

Figure 9

Chuzhoi mutants genetically interact with loop-tail and crash but not circletail. (A-C) Intercrosses of chuzhoi with Vangl2Lp/+, ScribCrc/+and Celsr1Crsh/+ generated doubly heterozygous fetuses with either no overt phenotypic abnormality (A), craniorachischisis (B) or lumbosacral spina bifida (arrow, C). (D) Graphical representation of the proportion of doubly heterozygous embryos demonstrating each phenotype; the number of double mutants examined is given at the top of each column.

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