Figure 5From: The novel mouse mutant, chuzhoi, has disruption of Ptk7 protein and exhibits defects in neural tube, heart and lung development and abnormal planar cell polarity in the earChuzhoi mutants exhibit abnormal lung development. (A, D) Examination of the gross morphology of the lungs from E18.5 wild-type (A) and chuzhoi mutant (D) fetuses showed small and misshapen lobes in the mutants. (B, C, E, F) Haemotoxylin and eosin-stained sections through the left lobe from wild-type (B, C) and chuzhoi mutant (E, F) E18.5 fetuses detected thickened interstitial mesenchyme and reduced sepatation in chuzhoi mutants.Back to article page