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Figure 5 | BMC Developmental Biology

Figure 5

From: The novel mouse mutant, chuzhoi, has disruption of Ptk7 protein and exhibits defects in neural tube, heart and lung development and abnormal planar cell polarity in the ear

Figure 5

Chuzhoi mutants exhibit abnormal lung development. (A, D) Examination of the gross morphology of the lungs from E18.5 wild-type (A) and chuzhoi mutant (D) fetuses showed small and misshapen lobes in the mutants. (B, C, E, F) Haemotoxylin and eosin-stained sections through the left lobe from wild-type (B, C) and chuzhoi mutant (E, F) E18.5 fetuses detected thickened interstitial mesenchyme and reduced sepatation in chuzhoi mutants.

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