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Table 1 Expression pattern of Mpl protein in the developing and adult mouse brain.

From: Expression pattern of the thrombopoietin receptor (Mpl) in the murine central nervous system

Subdivisions

E18.5

P0

P4

P7

Adult

Spinal cord

     

Cervical

Grey matter

++

++

++

+/-

++

 

White matter

-

-

-

-

-

Rhombencephalon

     

Myelencephalon

Roof plate, cochlear complex

+

++

+

-

++

 

Medulla, r2-r8

+

++

+

+/-

++

Metencephalon

Pons, r1

+

++

+

+

++

 

Cerebellar white matter

-

++

+

+

-

 

Cerebellar cortex +

external granule layer

-

-

-

-

-

 

Purkinje cells of cerebellum

-

-

-

-

+

Midbrain

     

Mesencephalon

Prepontine hindbrain

-

+

+

+

+

 

Tegmentum

+

++

-

+

++

 

Inferior colliculus

+

++

+

+/-

++

 

Superior colliculus

++

++

+

+/-

++

Prosencephalon

     

Diencephalon

Prethalamus

++

++

+

+/-

+

 

Thalamus

++

++

++

+

++

 

Pretectum

+

++

+

+

+

 

Preoptic area

++

++

+

-

++

 

Hypothalamus

+

++

+

+

+

Telencephalon

Basal ganglia

-

+

+

+/-

+

 

Hippocampal formation

-

-

+/-

++

+

 

Cerebral cortex, subventricular zone

-/+

++

-

-

-

 

Cerebral cortex

+

+

+

+

+

 

Olfactory bulb

+

+

-

-

+

  1. The rough estimates of the staining intensity are presented in different brain regions between E18.5, one day before birth, early postnatal stages as well as in the adult brain.