Figure 1
From: Changes in creatine transporter function during cardiac maturation in the rat
Total creatine content and creatine transporter mRNA in rat heart during maturation. A). Myocardial total creatine content in rats aged -2, 7, 13, 21, 33, 50 and 80 day old. B) Creatine transporter (CrT) mRNA levels in rat heart during maturation. Total RNA was isolated from foetal hearts on day 20 of gestation (2 d before birth), and 7, 21, 33, 50 and 80 d after birth. The level of CrT mRNA was measured by real-time RT-PCR and normalized to β-actin. Values are mean ± S.E. and sample size are given in brackets on the labels of the X axis. Data points not sharing the same superscript letter indicate total creatine and mRNA level respectively are significantly different to all others (p < 0.05 Bonferroni, ANOVA "test for linear trend": p < 0.001).