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Figure 6 | BMC Developmental Biology

Figure 6

From: Gene trap mutation of murine Outer dense fiber protein-2 gene can result in sperm tail abnormalities in mice with high percentage chimaerism

Figure 6

Abnormal ODF morphology in elongated spermatids of high percentage XL169 chimaeric males. To study the possible basis for the infertility of high percentage XL169 chimaeric mice, we carried out an ultrastructural electron microscopic analysis of samples from testis in a comparison to testis from low-medium percentage XL169 chimaeric mouse. Panel A shows an example of connected step 14-15 spermatids belonging to one syncytium, some of which appear normal (star), others lack ODF (arrows). Panel B shows two examples of abnormal midpieces from step 16 spermatids, one of which misses five ODF. Panel C shows step 16 spermatid midpieces from a low-medium percentage XL169 chimaeric mouse that appear normal. Magnification is 28,000 ×.

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BMC Developmental Biology

ISSN: 1471-213X

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