Expression pattern of E-cadherin in first-generation teeth. Left panels: mRNA expression; middle panels: protein expression; right panels: diagram of different cell layers of the tooth. A, B, C: Initiation phase. D, E, F: Morphogenesis phase; G, H, I: Early cytodifferentiation and attachment phase; J, K, L: Late cytodifferentiation phase and initiation of successor. ph.c.: pharyngeal cavity; ph.e.: pharyneal epithelium; *: dental papilla; arrowhead: enamel organ; block arrow: initiation replacement tooth. Diagrams: green cells: pharyngeal epithelium; red cells: outer dental epithelium; blue cells: inner dental epithelium. Scale bars = 2 5 μm.