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Table 3 Lists of genes tested for possible interaction with ten-1.

From: C. elegans ten-1 is synthetic lethal with mutations in cytoskeleton regulators, and enhances many axon guidance defective mutants

Gene(allele)

Allele type

Function/pathway

mig-14(ga62)

hypomorph

Wnt-secretion factor

sax-3(ky123)

null

receptor/robo slit

slt-1(e15)

null

ligand/robo slit

unc-5(e53)

null

receptor/netrin

unc-6(ev400)

null

ligand/netrin

unc-34(e315)

nonsense

Enabled VASP homolog/netrin and robo

unc-40(e271)

null

receptor/netrin

unc-51(e369)

dominant negative

serine threonine kinase

unc-52(e1421)

possible null

perlecan homolog

unc-73(e396)

null

guanine nucleotide exchange factor

unc-129(ev554)

null

secreted TGF-β