Figure 6

Feto-placental vasculature of DelTel7/IC2KO placentae at E14.5. A) Representative scanning electron micrographs of DelTel7/IC2KO fetal vasculature casts of whole placentae (n = 4) compared with B) wild type litter mates (n = 4). C) In-depth view of fetal capillaries of DelTel7/IC2KO compared with D) wild type. E) Morphometric analysis of fetal capillary diameters between DelTel7/IC2KO (Δ/IC2KO; 226 measurements from 4 placentae) and wild type (+/+; 144 measurements from 4 placentae) placentae. Scale bar for A) and B) = 1 mm. Scale bar for C) and D) = 250 microns. Note that in B) the umbilical vein has been dissected away at the primary branch points.