Figure 7
From: Conditional expression of Spry1 in neural crest causes craniofacial and cardiac defects
fgf8 expression is unaffected in Spry1;Wnt1-Cre embryos. (A) Lateral view and (B) frontal view to show the similarity in pattern and intensity of fgf8 expression in both WT and Spry1Wnt1-Cre (Spry1) E10.5 embryos. (C) Dorsal view showing the similarity of expression of fgf8 in otic placode both in WT and Spry1;Wnt1-Cre embryos, however overexpression of Spry1 resulted in a reduced and abnormal midbrain-hindbrain boundary. Data are representative of three independent experiments.