Figure 3
From: Cell cycle arrest by a gradient of Dpp signaling during Drosophila eye development
Graded requirement for Dpp and Hh signal transduction. This summary cartoon illustrates in the extent of cell cycle activity near the morphogenetic furrow in various genotypes. Green shading indicate regions where cells have progressed past the G1-S boundary, as indicated by CycB protein levels, for example, whereas white indicates regions where all cells remain in G1. In the case of wild type, shown at the top, all cells remain in G1 from anterior to the morphogenetic furrow until the Second Mitotic Wave starts, after which only the five cells of the photoreceptor preclusters remain in G1. These preclusters appear as the white circles in the Second Mitotic Wave pattern shown at the right of the diagram. Results from 11 other genotypes are summarized in order of severity, with the most severe at the bottom. In each case the approximate extent of the delay in G1 arrest that is observed in mutant clones is indicated. For simplicity, delays in the SMW that result from some genotypes are not included.