Table 2 Suture closure in Apert syndrome mice
From: Activation of p38 MAPK pathway in the skull abnormalities of Apert syndrome Fgfr2+P253R mice
| Fusion | ||||
|---|---|---|---|---|
| Sutures |
+/P253R (n = 10) |
+/+ littermate (n = 7) |
+/S252W (n = 8) |
+/+ littermate (n = 12) |
| closed/total* | closed/total | closed/total | patent/closed | |
| Coronal (bi- or unicoronal) | 9/10 | 0/7 | 7/8 | 0/12 |
| Zygomatic-maxillary | 10/10 | 0/7 | 7/8 | 0/12 |
| Maxilla-premaxillary | 10/10 | 0/7 | 8/8 | 0/12 |
| Inter-premaxillary | 0/10 | 7/7 | 1/8 | 11/12 |
| Inter-palatine | 0/10 | 2/7 | 0/8 | 3/12 |
| Maxillary-palatine | 1/10 | 4/7 | 7/8 | 5/12 |