Characterization of the astacin family of metalloproteases in C. elegans

Park, Ja-On; Pan, Jie; Möhrlen, Frank; Schupp, Marcus-Oliver; Johnsen, Robert; Baillie, David L; Zapf, Richard; Moerman, Donald G; Hutter, Harald

doi:10.1186/1471-213X-10-14

BMC Developmental Biology

Table 1 Astacin expression according to GFP reporter constructs

From: Characterization of the astacin family of metalloproteases in C. elegans

gene	sub group	pharynx	intestine	hypodermis	muscle	neurons	other
nas-1	I	mu, mc					arcade cells
nas-2	I		all cells				rectal glands, 2 cells in the head
nas-3	I	mu3-5	all cells	hyp1, seam (weak)		PDE	ILso?
nas-4	I	mc (weak)
nas-5	I	mc, glands					rectal glands, utse
nas-6	II	mu, mc2	all cells	major hyp	body wall muscle
nas-7	II	mu, mc	all cells	seam (strong), other hyp (weak)			arcade cells, spermatheca, vulva, rectal epithelial cells,
nas-9	II			major hyp			uterus, spermatheca
nas-11	II		anterior most cells	major hyp			CEPsh, AMsh, PHsh
nas-12	II	glands
nas-13	II					IL2L/R 1 pair of amphid neurons
nas-14	II	mu, mc
nas-15	II	mc mu3-6
nas-16	III		anterior most cells
nas-19	III	mu, mc	all cells				rectal glands, spermatheca
nas-21	III		all cells	major hyp (weak)			utse, gonad
nas-22	III						utse
nas-23	III	mu (weak)	weak, all cells	major hyp			rectum
nas-25	III	mc					rectal gland cells, pha-int valve, arcade cells
nas-26/toh-1	III		weak, all cells	major hyp			uterus, vulva epithelium, AMsh, arcade cells, PHsh, rectal epithelium
nas-27	III		all cells	major hyp			vulva epithelium, rectal epithelium
nas-28	III	mu	all cells				coelomocytes
nas-30	III		all cells	rectal epithelial cells
nas-31	IV						exc. cell, AMsh, PHsh,
nas-32	IV	mu			anal depressor muscle, intestinal muscle, vulva muscle	unidentified head neurons	head mesodermal cell
nas-33	V		all cells	tail hyp
dpy-31/nas-35	V		weak, all cells	major hyp			vulva epithelium, rectal epithelium, AMsh, IL/OLso, exc. duct cell
nas-37	V		weak, all cells	major hyp incl. seam (weak), rectal epi. cells			vulval epithelium, rectal epithelium
nas-39	VI	mu	all cells		vulva muscle, bwm,	many/most neurons

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ISSN: 1471-213X

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