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Figure 8 | BMC Developmental Biology

Figure 8

From: Balanced Shh signaling is required for proper formation and maintenance of dorsal telencephalic midline structures

Figure 8

Cell autonomous Shh-activated roof plate expansion causes Wnt3a expansion into choroid plexus domain. RNA in situ hybridization analysis of E12.5 wild type littermate control (A-C) and activated Smoothened expressed in the roof plate through GDF7cre regulation (D-F). Wnt3a: A, D, rTTR: B, E, Lhx5: C, F. n = 3. Arrows point to Wnt3a expansion (D) and rTTR expansion (E). Scale bar in A represents 200 μm and all panels in this figure are photographed at the same magnification (5×).

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BMC Developmental Biology

ISSN: 1471-213X

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