Figure 6
Activated ShhN from the endogenous Shh source expands dorsal midline telencephalic cortical hem, plexus and roof plate. RNA in situ hybridization analysis of E12.5 wild type littermate control (A-C) and ShhN/+ (D-F) telencephalon. Wnt3a: A, D, rTTR: B, E, Lhx5: C, F. n = 3. Scale bar in A represents 200 μm and all panels in this figure are photographed at the same magnification (5×).