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Figure 1 | BMC Developmental Biology

Figure 1

From: Balanced Shh signaling is required for proper formation and maintenance of dorsal telencephalic midline structures

Figure 1

Relationship of Shh and dorsal telencephalic midline markers at E10.5, E11.5, and E12.5. RNA in situ hybridization analysis of dorsal midline telencephalic genes, Wnt3a, rTTR, Lhx5, and ventral midline expression of Shh. Coronal sections [A-L], sagittal sections (M-T). E10.5 (A-D), E11.5 (E-H), and E12.5 (I-T). Scale bars = 200 μm. U is a schematic depicting the regional boundaries corresponding to the observed gene expression domains in a coronal section at mouse embryonic day 12.5. D, Dorsal, V, Ventral, R, Rostral, C, Caudal.

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