TY - JOUR AU - Himmelstein, Diana S. AU - Bi, Chunming AU - Clark, Brian S. AU - Bai, Brian AU - Kohtz, Jhumku D. PY - 2010 DA - 2010/11/29 TI - Balanced Shh signaling is required for proper formation and maintenance of dorsal telencephalic midline structures JO - BMC Developmental Biology SP - 118 VL - 10 IS - 1 AB - The rostral telencephalic dorsal midline is an organizing center critical for the formation of the future cortex and hippocampus. While the intersection of WNTs, BMPs, and FGFs establishes boundaries within this critical center, a direct role of Shh signaling in this region remains controversial. In this paper we show that both increased and decreased Shh signaling directly affects boundary formation within the telencephalic dorsal midline. SN - 1471-213X UR - https://doi.org/10.1186/1471-213X-10-118 DO - 10.1186/1471-213X-10-118 ID - Himmelstein2010 ER -