Figure 8

Spleen immunophenotyping of Lc3 synthase-knockout mice. Mouse spleen immunophenotype analysis showing the fluorescence intensity of the staining of four antibodies: The intensity from T-cell antibodies (CD4 and CD8) was normal in the Wt/KO or KO/KO phenotype as compared to that in the Wt/Wt phenotype; that for NK cell antibody (CD49b) in the Wt/KO or KO/KO phenotype was similar to that of the Wt/Wt phenotype, with P ≥ 0.05; and that for B cells (CD19) in the Wt/KO or KO/KO phenotype was reduced by about 39% when compared to that of the Wt/Wt phenotype, with P < 0.001.