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Figure 5 | BMC Developmental Biology

Figure 5

From: Multiple phenotypic changes in mice after knockout of the B3gnt5gene, encoding Lc3 synthase—a key enzyme in lacto-neolacto ganglioside synthesis

Figure 5

Early-stage growth delay of dwarfism in mice following Lc3 synthase knockout. The breeding was set in a heterozygote-heterozygote (+/-, +/-) base. Pups were weighed periodically. Mice of normal weight were weaned at day 21, and mice weighing <10 g were kept in the parental cage. The average weight of the same-litter control differs significantly from that of the dwarf B group (P = 0.0008), but differs less from that of the dwarf A group (P = 0.1072). Composition of the three mouse groups: Same-litter control (■): one +/+, two -/+, and one -/-; dwarf A group (□): two -/+; dwarf B group (): two -/+.

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