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Table 3 Epistasis between cdt-2 and components of the EGF signalling cascade

From: The Caenorhabditis elegansCDT-2 ubiquitin ligase is required for attenuation of EGFR signalling in vulva precursor cells

 

(RNAi) cdt-2

no RNAi

genotypes

Muv %

Vul %

VPCs (N)

Muv %

Vul %

VPCs (N)

lin-3(n378)

0

81

0.83 (75)

0

98

0.49 (75)

let-23(sy1)**

7

58

1.97 (46)

0

87

0.72 (30)

let-60(n1046)***

96

0

4.86 (24)

66

0

3.70 (30)

lin-45(n2018)

0

28

2.43 (36)

0

17

2.68 (30)

lin-3(n378);gap-1(n1691)

0

3

2.97 (60)

0

10

2.77 (60)

let-23(sy1);gap-1(ga133)***

90

0

4.50 (50)

70

0

3.80 (50)

lin-45(n2018);gap-1(n1691)

0

10

2.88 (30)

0

7

2.95 (30)

  1. ***P < 0.001, **P < 0.01