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Table 1 cdt-2 interacts with gap-1 to produce the Muv (Multiple vulvae) phenotype

From: The Caenorhabditis elegansCDT-2 ubiquitin ligase is required for attenuation of EGFR signalling in vulva precursor cells

 

cdt-2(RNAi)

no RNAi

genotypes

Muv %

VPCs (N)

Muv %

VPCs (N)

N2

gap-1(n1691)

0

43

3.0 (30)

3.4 (76)

0

0

3.0 (many)

3.0 (30)

lin-15A(n767)

7.5

3.1 (40)

0

3.0 (many)

lin-15B(n744)

2

3.0 (55)

0

3.0 (many)

lin-15AB(n765) a

33

3.3 (30)

13

3.1 (30)

  1. aTemperature sensitive allele maintained at 15°C
  2. Animals are Muv if more than 3 VPCs (Vulval Precursor Cells) adopt the vulval fate
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BMC Developmental Biology

ISSN: 1471-213X

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