Figure 1

Spatiotemporal expression patterns of dmbx1a and dmbx1b at 72 hpf and 96 hpf. Lateral view, anterior to the left (A, C, I, K); dorsal view, anterior to the top (B, D, J, L). Coronal plastic sections (~1 μm; dorsal to the top) of the retina (E, G, M, O) and midbrain (F, H, N, P) were obtained after whole mount labeling with RNA probes. White dotted line in B and D define the position of the representative coronal plastic section shown in F and H, respectively. White dotted line in J and L define the position of the representative coronal plastic section shown in N and P, respectively. White arrow in B, D, J, L demarcates the rostrolateral region of the hindbrain (where the EG is located), and red arrow demarcates the expression in the medulla oblongata. Black arrows in E, M and O point to the INL (inner nuclear layer). The optic tectum (TeO) is demarcated by dotted lines in F, H, N, P and the region of the tegmentum (T) lies just ventral to the TeO. The position of the lens is denoted in E, G, M, O. hpf, hours post-fertilization.